Betekenis van:
monoclonal

monoclonal
Bijvoeglijk naamwoord
  • monoclonaal
  • forming or derived from a single clone
monoclonal
Zelfstandig naamwoord
    • any of a class of antibodies produced in the laboratory by a single clone of cells or a cell line and consisting of identical antibody molecules

    Synoniemen

    Hyperoniemen

    Hyponiemen


    Voorbeeldzinnen

    1. Antibodies, monoclonal, polyclonal or anti-idiotypic;
    2. microplate based immunoassay (ELISA) which detects Proteinase Kresistant PrPRes with monoclonal antibodies (Prionics-Check LIA test),
    3. microplate based immunoassay (ELISA) which detects protease resistant PrPRes with monoclonal antibodies (Prionics-Check LIA test),
    4. Detection of measles virus antigen by DFA in a clinical specimen using measles specific monoclonal antibodies
    5. Perform an appropriate ELISA procedure with a specific monoclonal antibody to R. solanacearum.
    6. lateral flow immunoassay using two different monoclonal antibodies to detect Proteinase K resistant PrP fractions (Prionics Check PrioSTRIP),
    7. Always use a polyclonal antibody for IF screening, additional monoclonal antibodies may provide more specifity (see section 4).
    8. Detection of Legionella pneumophila antigen in respiratory secretions or lung tissue e.g. by DFA staining using monoclonal-antibody derived reagents
    9. Add 50 μl/well of pre-diluted horseradish-peroxidase (HRP) -conjugated Mab (monoclonal antibodies specific for VP7) to each well and mix gently to ensure homogeneity.
    10. antigen-capture ELISA using two different monoclonal antibodies to detect Proteinase K-resistant PrP fractions (Fujirebio FRELISA BSE post-mortem rapid BSE Test).
    11. When DAS ELISA is used enrichment and the use of monoclonal antibodies are compulsory (see web site http://forum.europa.eu.int/Public/irc/sanco/Home/main).
    12. Enrichment Double-Antibody Sandwich Indirect Enzyme-Linked Immunosorbent Assay That Uses a Specific Monoclonal Antibody for sensitive Detection of Ralstonia solanacearum in Asymptomatic Potato Tubers.
    13. "Immunotoxin" (1) is a conjugate of one cell specific monoclonal antibody and a "toxin" or "sub-unit of toxin", that selectively affects diseased cells.
    14. two-sided immunoassay using two different monoclonal antibodies directed against two epitopes presented in a highly unfolded state of bovine PrPSc (Roboscreen Beta Prion BSE EIA Test Kit),
    15. the two-sided immunoassay using two different monoclonal antibodies directed against two epitopes presented in a highly unfolded state of bovine PrPSc (Roboscreen Beta Prion BSE EIA Test Kit),